Nucleic Acids

Nucleic Acids – The Blueprint of Life

Nucleic acids are fundamental biomolecules responsible for the storage, transmission, and expression of genetic information in all living organisms. They are rightly called the blueprint of life because they control heredity, cellular functions, and protein synthesis.

Table of Contents

Introduction

Nucleic acids are high-molecular-weight organic compounds found in all living cells. They store genetic instructions and ensure their accurate transmission from one generation to the next.

The two main nucleic acid are DNA (Deoxyribonucleic Acid) and RNA (Ribonucleic Acid).

Types

1. DNA (Deoxyribonucleic Acid)

  • Stores hereditary information
  • Controls cell structure and function
  • Found mainly in the nucleus

2. RNA (Ribonucleic Acid)

  • Helps in protein synthesis
  • Transfers genetic information from DNA
  • Present in nucleus and cytoplasm

Structure

Both DNA and RNA are polymers made up of repeating units called nucleotides.

Each nucleotide consists of:

  • Nitrogenous base
    • Purines: Adenine (A), Guanine (G)
    • Pyrimidines: Cytosine (C), Thymine (T – DNA), Uracil (U – RNA)
  • Pentose sugar (Deoxyribose in DNA, Ribose in RNA)
  • Phosphate group

DNA – The Blueprint of Life

DNA is a double-stranded, helical molecule that contains the complete genetic instructions required for the development and functioning of organisms.

Nucleic Acids
Nucleic Acids
  • Bases: Adenine (A), Thymine (T), Cytosine (C), Guanine (G)
  • Base pairing: A–T and C–G
  • Held together by hydrogen bonds
  • Located in the nucleus (eukaryotes)

RNA – The Messenger Molecule

RNA is usually single-stranded and plays a vital role in translating genetic information into proteins.

Types of RNA

TypeFunction
mRNACarries genetic code from DNA to ribosome
tRNATransfers amino acids during protein synthesis
rRNAForms structural part of ribosome

Functions

  • Storage of genetic information
  • Protein synthesis
  • Regulation of gene expression
  • Transmission of hereditary traits

Biological Importance

Without nucleic acid, life cannot exist. They maintain continuity of life, control metabolism, and ensure accurate reproduction.

Biomolecules | Proteins | Carbohydrates

Frequently Asked Questions

What are nucleic acid?

Nucleic acid are biomolecules that store and transmit genetic information.

Difference between DNA and RNA?

DNA stores genetic information permanently, while RNA helps in protein synthesis.

Why are nucleic acid important?

They control heredity, protein formation, and cellular activities.

Quiz

MCQs

1. Which sugar is present in DNA?
b) Deoxyribose

2. Which base is present in RNA but absent in DNA?
b) Uracil

True / False

DNA contains uracil – False

RNA plays a role in protein synthesis – True

Fill in the Blanks

DNA is made of __________ → Nucleotides

In RNA, thymine is replaced by __________ → Uracil

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